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Organisation
Newsflash
Starthilfe von Grand Challenges Explorations (ETH life)
Symposium
 Head: Prof. Gisbert Schneider |
The computer-assisted drug design group
develops and implements concepts, algorithms and software for rapid
identification
of bioactive molecules and pharmaceutical lead compounds. The molecular
design
cycle involves multiple scientific disciplines and requires rigorous
trans-disciplinary thinking. |
 Head: Prof. Cornelia Halin |
We are investigating how leukocytes transmigrate through lymphatic endothelium. An important goal of our research is to identify and validate new (adhesion) molecules, which could serve as therapeutic targets to modulate immune responses. |
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Head: Prof. Jean-Christophe Leroux |
Pharmaceutical and biomedical engineering of formulations and delivery systems for peptide and protein therapeutics, vaccines, and gene medicines. |
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Pharmaceutical Analytics Head: Dr. Irmgard Werner |
Sterilization of drugs and drug-systems by ionizing radiation. Stability and purity testing on new drugs and drug-formulations. Drafting of monographs for Pharmacopoeias. Development of new analytical strategies and methods. |
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Pharmaceutical Biology Head: Prof. Karl-Heinz Altmann |
Chemical synthesis and biological profiling of natural products and their synthetic and semi-synthetic analogs. Our research aims to understand the mechanisms of action of biologically active natural products and to elucidate the structural requirements for biological activity. |
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Head: Prof. Jonathan Hall |
Study of protein-ligand interactions by means of molecular modeling and QSAR technologies closely integrated with biophysical analytics and protein crystallography. |
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Head: Prof. Michael Detmar |
Identification and validation of molecular targets controlling angiogenesis and lymphangiogenesis associated with cancer progression and with inflammation. Characterization of genetic polymorphisms that determine disease susceptibility, and development of individualized therapeutic strategies. |
 Haed: Prof. Hanns Ulrich Zeilhofer |
At present we focus on the contribution of inhibitory GABAergic and glycinergic neurotransmission to spinal pain control mechanisms. To address these topics we employ a multidisciplinary approach including electrophysiological recordings and functional imaging in spinal cord slices as well as the generation of genetically modified mice and their analysis in behavioral tests |
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Biopharmacy Head: PD Dr. Stefanie Krämer |
Cell biological and physico-chemical aspects of the absorption, distribution and elimination of drugs. The focus is on drug interactions with biological and artificial membranes and transport mechanisms. | |
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Radiopharmaceutical Science Head: Prof. Pius Schubiger |
Targeted radiotherapeutics, properties of molecular targets, radioimmunoconjugates, radionuclide labelling techniques; PET- tracerchemistry and - pharmacology , drug development, animal PET methodology |
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Head: Prof. Roger Schibli |
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