 |
|
2000-2003
2003
2002
- Krämer, S.
D., Schutz, Y. B, Wunderli-Allenspach, H, Abbott, N. J., Begley, D. J. (2002) Lipids in blood-brain barrier models
in vitro II: Influence of glial cells on lipid classes and lipid fatty acids. In Vitro Cell. Dev. Biol.-Animal 38, 566-71.
- Niesner,
U., Halin C., Lozzi, L., Günthert, M., Neri, P., Wunderli-Allenspach, H.,
Zardi, L., Neri, D. (2002) Quantitation of the tumor-targeting
properties of antibody fragments conjugated to cell-permeating HIV-1 TAT peptides. Bioconjugate Chem., 13, 729-736.
- Pietzonka,
P., Rothen-Rutishauser, B., Langguth P., Wunderli-Allenspach, H., Walter, E.,
Merkle, H. P. (2002) Transfer of lipophilic markers from
PLGA and polystyrene nanoparticles to Caco-2 monolayers mimics particle uptake. Pharm. Res. 19, 595-601.
- Riesen,
F. K., Rothen-Rutishauser, B., Wunderli-Allenspach, H. (2002) A ZO1-GFP fusion protein to study
the dynamics of tight junctions in living cells. Histochem. Cell Biol. 117, 307-315.
- Rothen-Rutishauser,
B., Riesen, F. K., Braun, A., Günthert, M., Wunderli-Allenspach, H. (2002) Dynamics of tight and adherens
junctions under EGTA treatment.
J. Memb. Biol. 188, 151-162.
- Schwarzwald,
C. C., Feige, K., Wunderli-Allenspach, H., Braun, U. (2002) Comparison
of pharmacokinetic variables for two low-molecular-weight heparins after
subcutaneous administration of a single dose to horses. Am. J. Vet. Res. 63, 868-873.
- Suda,
K., Rothen-Ruthishauser, B., Günthert, M., Wunderli-Allenspach, H. (2002)
Response to the report by Drexler et al. In Vitro Cell. Dev. Biol.-Animal 38,
187
2001
- Wunderli-Allenspach,
H. (2001) Methodologies in cell culture. In: Pharmacokinetic Optimization in
Drug Research: Biological, Physicochemical and Computational Strategies. Eds. B. Testa, H. van de Waterbeemd, G. Folkers and R. Guy. Wiley-VCH, Weinheim.
- Beyer,
U., Rothen-Rutishauser, B., Unger, C., Wunderli-Allenspach, H., and Kratz, F.
(2001) Differences
in the intracellular distribution of acid-sensitive doxorubicin-protein conjugates
in comparison to free and liposomal formulated doxorubicin as shown by confocal
microscopy. Pharm. Res., 18, 29-38.
- Langer,
M., Kratz, F., Rothen-Rutishauser, B., Wunderli-Allenspach, H., and
Beck-Sickinger, A. G. (2001) Novel peptide conjugates for
tumor-specific chemotherapy.
J. Med. Chem., 44, 1341-1348.
- Krämer,
S. D., and Wunderli-Allenspach, H. (2001) Physicochemical
properties in pharmacokinetic lead optimization. Farmaco, 56, 145-148.
- Suda,
K., Rothen-Rutishauser, B., Günthert, M., and Wunderli-Allenspach, H. (2001) Phenotypic characterization of human
umbilical vein endothelial (ECV304) and urinary carcinoma (T24) cells:
Endothelial versus epithelial features. In Vitro Cell. Dev. Biol.-Animal, 37, 505-514.
- Thiele,
L., Rothen-Rutishauser, B., Jilek, S., Wunderli-Allenspach, H., Merkle, H. P.,
and Walter, E. (2001) Evaluation of particle uptake in
human blood monocyte-derived cells in vitro. Does phagocytosis activity of
dendritic cells measure up with macrophages? J.
Control. Release, 76, 59-71.
2000
- Beermann,
C., Wunderli-Allenspach, H., Groscurth, P., and Filgueira, L. (2000) Lipoproteins from Borrelia
burgdorferi applied in liposomes and presented by dendritic cells induce CD8+
T-lymphocytes in vitro.
Cell. Immunol. 201, 124-131.
- Cattaneo-Pangrazzi,
R. M. C., Schott, H., Wunderli-Allenspach, H., Rothen-Rutishauser, B.,
Günthert, M., and Schwendener, R. A. (2000) Cell cycle arrest and
p53-independent induction of apoptosis by the new anticancer drugs
5-FdUrd-P-FdCydOct and dCydpam-P-FdUrd in DU-145 human prostate cancer cells. J. Cancer Res. Clin. Oncol. 126, 247-256.
- Cattaneo-Pangrazzi,
R. M. C., Schott, H., Wunderli-Allenspach, H., Derighetti, M. I., and
Schwendener, R. A. (2000) Induction
of cell cycle-dependent cytotoxicity and apoptosis by new heterodinucleoside
phosphate dimers of 5-fluorodeoxyuridine in PC-3 human prostate cancer cells.
Biochem. Pharmacol., 60, 1887-1896.
- Friebe,
M., Suda, K., Spies, H., Syhre, R., Berger, R., Johannsen, B, Efstratios, C.,
Krämer, S. D., Wunderli-Allenspach H. (2000) Permeation
studies in vitro and in vivo of potential radiopharmaceuticals with affinity to
neuro receptors. Pharm. Res. 17, 754-760.
- Hämmerle,
S. P., Rothen-Rutishauser, B., Krämer, S. D., Günthert, M., Wunderli-Allenspach,
H. (2000) P-Glycoprotein
in cell cultures: a combined approach to study expression, localisation, and functionality
in the confocal microscope. Eur. J. Pharm. Sci., 12, 69-77.
- Rothen-Rutishauser,
B., Braun, A., Günthert, M., Wunderli-Allenspach, H. (2000) Formation
of multilayers in the Caco-2 cell culture model: A confocal laser scanning
microscopy study. Pharm. Res. 17, 460-465.
- Braun,
A., Hämmerle, S. P., Suda, K., Rothen-Rutishauser, B., Günthert, M., Krämer, S.
D., Wunderli-Allenspach, H. (2000) Cell
cultures as tools in biopharmacy. Eur. J. Pharm. Sci., 11 Suppl. 2,
S51-S60.
- Fabry,
M., Langer, M., Rothen-Rutishauser, B., Wunderli-Allenspach, H., Höcker, H.,
Beck-Sickinger, A. (2000) Monitoring
of the internalization of neuropeptide Y on neuroblastoma cell line SK-N-MC.
Eur. J. Biochem. 267, 5631-5637.
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