Teaching activities

The Biopharmacy group is committed to excellence in teaching.

The contents of the lectures and practical course are

Biopharmacy 1 and 2 (535-0241-01L and 535-0241-02L, lecture)

• introduction to biopharmacy in general and to basic pharmacokinetics
• interpretation of concentration/time profiles
• competence for designing therapeutic regimens
• risk assessment in individuals with monotherapies as well as in the cases of comedication with two or more drugs
• potential of pharmacokinetics for individual drug therapy and for the development of adequate drug formulations

Biotransformation of Drugs and Xenobiotics (535-0250-00L, lecture)

• introduction to drug and xenobiotic metabolism reactions and the responsible enzymes
• recognition of potentially toxic metabolites and potentially toxiphoric groups in a molecule
• mechanisms of bioactivation and toxification
• introduction to genetic variabilities in drug metabolism and their consequences
• introduction to inter-individual variabilities in drug metabolism, including drug-drug and food-drug interactions and consequences thereof

Laboratory Course in Biopharamcy (535-0240-00L, practical course)

• preparation of liver microsomes and study of a metabolism reaction
• determination of n-octanol/buffer partition coefficients, logP, logD
• characterization of serum albumin binding of a drug by equilibrium dialysis

For more details, see the Course Catalogue of the ETH >