1985-1993

Peptide Synthesis and Conformation

• K.-H. Altmann, M. Mutter, Chemie in unserer Zeit 1993, 27, 274 - 286.
  "Die Chemische Synthese von Peptiden und Proteinen" (Review).
• M. Mutter, G. G. Tuchscherer, C. Miller, K.-H. Altmann, R. I. Carey, D. F. Wyss, A. M. Labhardt, J. E. Rivier, J. Am. Chem. Soc. 1992, 114, 1463 - 1470.
  "Template Assembled Synthetic Proteins with Four-Helix-Bundle Topology. Total Chemical Synthesis and Conformational Studies".
• K.-H. Altmann, E. Altmann, M. Mutter, Helv. Chim. Acta 1992, 75, 1198 - 1210.
  "Conformational Studies on Petides Containing -Methyl -Amino Acids. 1. Differential HHelHelix Inducing Potential of (R)- and (S)-2-Methyl Aspartic Acid".
• M. Mutter, K.-H. Altmann, R. I. Carey, I. Ernest, R. Flögel, D. Wyss, S. Vuilleumier, J. E. Rivier, G. Tuchscherer, Peptides - Structure and Function, Proceedings of the 21st European Peptide Symposium, E. Giralt, D. Andreu, Eds., Escom Science Publishers B. V. 1991, 249 - 250.
  "New Approaches to Template Assembled Synthetic Proteins".
• R. I. Carey, K.-H. Altmann, M. Mutter, Ciba Foundation Symposium 158 on Host-Guest Molecular Interactions, Wiley, Chichester 1991, 187 - 203.
  "Protein Design: Template Assembled Synthetic Proteins".
• M. Mutter, U. Buttkus, R. Gassmann, K.-H. Altmann, Angew. Chem. Int. Ed. Engl. 1991, 30, 1514 - 1517.
  "Switch Peptides: pH-Induced -Helix to -Sheet Transitions of Bis-Amphiphilic Peptides".
• K.-H. Altmann, J. Wojcik, M. Vasquez, H. A. Scheraga, Biopolymers 1990, 30, 107 -120 .
  "Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water XXIII. Proline Parameters from Random Poly(hydroxybutyl-L-glutamine-co-L-proline)".
• J. Wojcik, K.-H. Altmann, H. A. Scheraga, Biopolymers 1990, 30, 121 - 134.
  "Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water XXIV. Half-Cystine Parameters from Random Poly(hydroxybutyl-L‑glutamine-co-S-methylthio-L-cysteine)".
• K.-H. Altmann, H. A. Scheraga, J. Am. Chem. Soc. 1990, 112, 4926 - 4931.
  "Formation of Local Structures in Bovine Pancreatic Ribonuclease A. Effect of Amino Acid Substitutions on the Preferential Formation of the Native Disulfide Loop in Synthetic Peptides Corresponding to the Amino Acid Sequence Cys 58 - Cys 72 in RNase A".
• K.-H. Altmann, M. Mutter, Int. J. Biochem. 1990, 22, 947 - 956.
  "A General Strategy for the De Novo Design of Proteins - Template Assembled Synthetic Proteins" (Review).
• M. Mutter, K.-H. Altmann, G. Tuchscherer, S. Vuilleumier, Tetrahedron 1988, 44, 771 - 785.
  "Strategies for the De Novo Design of Proteins".
• M. Mutter, E. Altmann, K.-H. Altmann, R. Hersperger, P. Koziej, K. Nebel, G. Tuchscherer, S. Vuilleumier, H.-U. Gremlich, K. Müller, Helv. Chim. Acta 1988, 71, 835 - 847.
  "The Construction of New Proteins III. Artificial Folding Units by Assembly of Amphiphilic Secondary Structures on a Template".
• E. Altmann, K.-H. Altmann, M. Mutter, Angew. Chem. 1988, 100, 855 - 856.
  "Synthesis of Peptides Containing (2S)-2-Methyl Serine".
• E. Altmann, K.-H. Altmann, K. Nebel, M. Mutter, Int. J. Pept. Protein Res. 1988, 32, 344 - 349.
  "Conformational Studies on Host-Guest Peptides containing -Methyl -Amino Acids - Comparison of the Helix-Inducing Potential of -Amino Isobutyric Acid, (2S)-2-Ethyl Alanine, and (2S)-2-Methyl Serine".
• M. Mutter, K.-H. Altmann, H. Gehrhardt, Reactive Polymers 1987, 6, 99 - 107.
  "Functionalized Polyethylene Glycols and Polypeptides in Organic Synthesis and Catalysis".
• M. Mutter, K.-H. Altmann, T. Vorherr, S. Vuilleumier, Peptides - Structure and Function, Proceedings of the 19th European Peptide Symposium, D. Theodoropoulos, Ed., de Gruyter, Berlin 1987, 307 - 310.
• K.-H. Altmann, A. Flörsheimer, M. Mutter, Int. J. Pept. Protein Res. 1986, 27, 314 - 319.
  "Sequence-Dependence of Secondary Structure Formation III: -structure forming potential of amphiphilic oligopeptides containing alternating L-Val-L-Thr and L-Leu-L-Ser residues".
• T. Vorherr, K.-H. Altmann, M. Mutter, Helv. Chim. Acta 1986, 69, 410 - 414.
  "Single-Centre Model for the Active Site of -Chymotrypsin".
• M. Mutter, K.-H. Altmann, A. Flörsheimer, J. Herbert, Helv. Chim. Acta 1986, 69, 786 -792.
  "Sequence-Dependence of Secondary Structure Formation IV: Helix-Forming Potential of Amphiphilic Oligopeptides containing Aib Residues".
• M. Mutter, K.-H. Altmann, K. Müller, S. Vuilleumier, T. Vorherr, Helv. Chim. Acta 1986, 69, 985 - 995.
  "Approaches to Synthetic Vaccines. Design of Epitope-Containing Amphiphilic Peptides Matching the Antigenic Structure in the Native Protein".
• M. Mutter, K.-H. Altmann, T. Vorherr, Z. Naturforsch. 1986, 41b, 1315 - 1322.
  "The Construction of New Proteins II. Design, Synthesis and Conformational Studies of Folding Units with -Topology".
• M. Mutter, K.-H. Altmann, Die Angewandte Makromolekulare Chemie 1986, 145/146, 211 - 229.
  "The Construction of New Proteins" (Review).
• M. Mutter, K.-H. Altmann, D. Bellof, A. Flörsheimer, J. Herbert, M. Huber, B. Klein, L. Strauch, T. Vorherr, H.-U. Gremlich, Peptides - Structure and Function, Proceedings of the 9th American Peptide Symposium, C. M. Deber,, V. J. Hruby, K. D. Kopple, Eds., Pierce Chemical Company, Rockford Ill 1986, 397 - 405.
• M. Mutter, F. Maser, K.-H. Altmann, C. Toniolo, G.M. Bonora, Biopolymers 1985, 24, 1057 - 1074.
  "Sequence-Dependence of Secondary Structure Formation: Conformational Studies of Host-Guest Peptides in -Helix and -Structure Supporting Media".
• M. Mutter, K.-H.Altmann, Int. J. Pept. Protein Res. 1985, 26, 373 - 380.
  "Sequence-Dependence of Secondary Structure Formation II: Effect of nearest neighbour interactions on the -structure formation of host-guest peptides".
• M. Mutter, K.-H. Altmann, J. Schmitt, Makromol. Chem., Rapid Commun. 1985, 6, 785 - 789.
  "Poly(ethylene glycol)-bound peptides as single centre models for enzyme-like catalysis".