Imig, Jochen, Dr.

ETH Zürich Dr. Jochen Imig Institut f. Pharmazeut. Wissenschaften HCI H 428 Wolfgang-Pauli-Str. 10 8093 Zürich Phone: +41 44 633 39 79 E-Mail:

Research Interests
• Post-transcriptional regulation of germ cell apoptosis in C. elegans by RNA-binding proteins and microRNAs
• Interplay of RNA-binding proteins and microRNA machinery in vascularization

Education and Positions held
2010 - present
Postdoctoral fellow, Group of Dr. A. Gerber and Prof. J. Hall, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland
2007 - 2009
PhD thesis with Prof. Friedrich Grässer, Saarland University Medical School, Institute of Virology, Germany (guest scientist at Department of Oncology, University Hospital Zurich; group of Prof. C. Renner)
Thesis title: “Identification and functional characterization of viral and cellular microRNA expression in EBV-associated B-cell lymphomas.”
2006 - 2007
Scientific employee at Department of Oncology, University Hospital Zurich, Switzerland
March - December 2005
Scientific employee at ResearchGroup Phosphosites, Department of Internal Medicine II, University of Saarland Medical School, Homburg/Saar, Germany
May - October 2004
Research associate at Department of Internal Medicine I, University of Saarland Medical School, Homburg/Saar, Germany, Group of Prof. C. Renner
2004
Diploma in biology. Diploma thesis: “Subject of thesis: Serological identification of tumor-specific antigens by an eukaryotic surface display system out of a mammary-carcinoma derived cDNA- expression library”
Supervisor: Prof. C. Renner, of Internal Medicine I, University of Saarland Medical School, Homburg/Saar, Germany
1998 - 2004
Undergraduate studies in biology at the University of Saarbrücken, Germany

Publications

• Imig J, Motsch N, Zhu JY, Barth S, Okoniewski M, Reineke T, Tinguely M, Faggioni A, Trivedi P, Meister G, Renner C, Grässer FA, (2010) microRNA profiling in Epstein-Barr virus-associated B-cell lymphoma. Nucleic Acids Res. Nov. 9.
• Jung V, Fischer E, Imig J, Kleber S, Nuber N, Reinshagen F, Kamradt J, Grobholz R, Knuth A, Renner C, Wadle A. (2010) Yeast-based identification of prostate tumor antigens provides an effective vaccine platform. Anticancer Res. 30(3): 895-902.
• Engel M., Hindie V., Lopez-Garcia LA., Stroba A., Schaeffer F., Adrian I., Imig J., Idrissova L., Nastainczyk W., Zeuzem S., Alzari PM., Hartmann RW., Piiper A., Biondi RM., (2006) Allosteric activation of the protein kinase PDK1 with low molecular weight compounds. EMBO J. 25(23): 5469-80
• Wadle A., Kubuschok B., Imig J. et al., (2006) Serological immune response to cancer testis antigens in patients with pancreatic carcinomas. Int J Can.119(1): 117-25
• Kiermayer S., Biondi RM., Imig J., Plotz G., Haupenthal J., Zeuzem S., Piiper A., (2005) Epac activation converts cAMP from a proliferative into a differentiation signal in PC12 cells. Mol Biol Cell. (12): 5639-48
• Wadle A., Mischo A., Henrich PP., Stenner-Liewen F., Scherer C., Imig J., Petersen G., Pfreundschuh M., Renner C., (2005) Characterization of Hap/BAG-1 variants as RP1 binding proteins with antiapoptotic activity. Int J Cancer. 117(6): 896-904.
• Serological identification of breast cancer related antigens from a Saccharomyces cerevisiae surface display library. Wadle A., Mischo A., Imig J., Wüllner B., Hensel D., Wätzig K., Neumann F., Kubuschok B., Schmidt W., Old LJ., Pfreundschuh M., Renner C. (2005) Int. J. Cancer 117(1): 104-13.