Proulx, Steven, Dr.

Research Interests

• Role of macrophages in mediating lymphangiogenesis in inflammation and cancer
• In vivo imaging of lymphatic function

Education & Positions held

2008 - present
Post-Doctoral Researcher, Institute of Pharmaceutical Science, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland, laboratory of Prof. Dr. Michael Detmar

2004 - 2007
Research Assistant, University of Rochester Medical Center, Rochester, NY, USA, Laboratory of Edward Schwarz, Center For Musculoskeletal Research

2003 - 2007
Ph.D., Biomedical Engineering, University of Rochester, Rochester, NY, USA Thesis: “In Vivo Imaging of TNF-Transgenic Murine Arthritis” Advisor: Edward M. Schwarz, PhD, Professor, Department of Orthopedics

2003 - 2004
Teaching Assistant, University at Rochester, Rochester, NY, USA

1998 - 1999
M.S., Biomechanical Engineering, Stanford University, Palo Alto, CA, USA

1994 - 1998
B.S., Mechanical Engineering, Binghamton University, Binghamton, NY, USA

Publications

2012
Proulx S, Detmar M. (2012) Watching lymphatic vessels grow by making them glow. Cell Research, 2: 12-3

2010
Mumprecht V, Honer M, Vigl B, Proulx ST, Trachsel E, Kaspar M, Banziger-Tobler NE, Schibli R, Neri D, Detmar M. In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography. Cancer Res, 70: 8842-51.

Proulx ST, Luciani P, Derzsi S, Rinderknecht M, Mumprecht V, Leroux J-Ch, Detmar M. Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green. Cancer Res, 70: 7053-62.

Huggenberger R, Ullmann S, Proulx ST, Pytowski B, Alitalo K, Detmar M. Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation. J Exp Med, 207: 2255-69.

2008
Proulx ST, E Kwok, Z You, MO Papuga, CA Beck, DJ Shealy, LM Calvi, CT Ritchlin, HA Awad, BF Boyce, L Xing, EM Schwarz. (2008) Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast enhanced MRI. Arthritis and Rheumatism, 58(7):2019-29.

Tsutsumi R, Hock C, Bechtold CD, Proulx ST, Bukata SV, Ito H, Awad H, Nakamura T, O’Keefe RJ, EM Schwarz (2008). Differential effects of biologic vs bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT. J Orthop Res., 26(10):1340-6.

2007
Proulx ST, E Kwok, CA Beck, DJ Shealy, CT Ritchlin, HA Awad, BF Boyce, L Xing, EM Schwarz. “Longitudinal Assessment of Synovial, Lymph Node, and Bone Volumes in Inflammatory Arthritis in Mice using in vivo MRI and micro-CT.” Arthritis and Rheumatism 2007; 56(12): 4024-4037.

Proulx ST, E Kwok, Z You, CA Beck, DJ Shealy, CT Ritchlin, BF Boyce, L Xing, EM Schwarz. “MRI and Quantification of Draining Lymph Node Function in Inflammatory Arthritis.” Ann. N.Y. Acad. Sci 2007; 1117:106-23.

Zhang Q, Y Lu, ST Proulx, R Guo, Z Yao, EM Schwarz, BF Boyce, L Xing. “Increased Lymphangiogenesis in Joints of Mice with Inflammatory-Erosive Arthritis.” Arthr Res Therapy 2007; 9:R118.