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The main focus of
our radiopharmacy research is the development of radioactively labeled
molecules which bind specifically to defined structures (e.g. receptors or
antigens) in vivo. Such functional radiopharmaceuticals can serve both as
diagnostic agents in nuclear medicine and as therapeutic agents for use against
tumor metastases.
The Center for Radiopharmaceutical Sciences is supported by ETH Zurich, the Paul
Scherrer Institute, Villigen and the University Hospital Zurich, and is working
towards clinical application of radiopharmaceuticals based on an
interdisciplinary approach involving radiopharmaceutical chemistry,
biochemistry, molecular biology, pharmacy and pharmacology.
The research focus at the Animal Imaging Center-PET located at the
ETH-Hönggerberg (Science City Campus) is functional molecular imaging with both
newly developed and established PET tracers using an integrated rodent PET/CT
and a small animal PET camera. At the USZ, the main activity is GMP-production
of newly developed PET tracers for clinical research, as well as GMP-production
of clinically established PET ligands for routine application in nuclear
medicine.
At the PSI with its powerful high energy cyclotron and respective
infrastructure, the main focus is on targeted radionuclide therapy from
fundamental research on potential new therapies through to preclinical
evaluation.
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